Vinpocetine, a semi-synthetic compound derived from the Periwinkle plant, has been used in Europe for over twenty-five years, mainly for the treatment of disorders of the brain. Numerous clinical trials and laboratory studies have been conducted to test the efficacy of vinpocetine, and, although a lot more work needs to be done, it appears that this natural supplement does have an important role to play in the treatment and/or prevention of several brain disorders and degenerative conditions.