Hyaluronic acid occurs throughout the body, but especially in nerve, skin and connective tissue. It is a vital ingredient to synovial fluid, which is found in the skin, joints and eyes. Hyaluronic acid lubricates the joints and helps to improve their mobility.
Making Hyaluronic Acid a part of your daily diet may help boost synovial fluid quality in both the skin and joints. It helps to reduce swelling and inflammation. This formula also includes MSM (methylsulfonylmethane) for its additional joint-relieving benefits.
MSM has been demonstrated by studies to be able to relieve inflammation and pain that is associated with rheumatoid arthritis and osteoarthritis. It helps to heal tendons and joints.
Hyaluronic acid or hyaluranan or hyaluronate is a glycosaminoglycan present in various tissues within the body like neural, epithelial and connective tissues. It is among the major components of the extracellular matrix and plays an important role in a cell’s migratory activities and proliferation. About one third of the hyaluronic acid present in the body is regenerated each day. Hyaluronic acid also forms an important part of the synovial fluid. It increasing its viscosity and lubricating capacity. Hyaluronic acid is present in articular cartilages as well. There it forms a covering of the chondrocytes. By reacting with aggrecan, it forms complexes with high negative charge that give cartilages their resilience by absorbtion of water by these complexes.
In the skin Hyaluronic Acid performs the task of repairing the tissues. Its role in the healing of the tissues in the eye after the removal of cataracts has been noted. It clears the way for white blood corpuscles to heal the tissues. It also helps the cells in the absorption and reception of various substances. In the presence of ultraviolet rays, the concentration of hyaluronic acid in the skin reduces. This may lead to sunburn and accumulation of the products of the decomposition in the skin. It also binds with receptors like TLR 2 and TLR 4 and provides the cells with an innate immunity. Degradation of hyaluronic acid is carried out by a number of enzymes called as hyaluronidases. These are usually used in drugs that suppress tumors in the body.
In particular methods of treatments like viscosupplementation, hyaluronic acid is used for treatment of osteoarthritis in a person's knee. These increase the viscosity of the fluid present in the joints and thus increase their lubricating capacity. By improving lubrication, it also acts as a pain reliever. Doses of hyaluronic acid are also said to have good effects on the cells of the cartilage. Recently, oral doses of hyaluronic acid have also been suggested. It is also gaining popularity in research for development of tissue cultures.
Usually, high levels of hyaluronic acid are detected in individuals suffering from various types of cancer. Thus, it is used to detect the severity of the tumor and the progress of the disease.
As hyaluronic acid can be directly manufactured in the form, in which it is present in the body, it has gained wide popularity in the field of medicine and related research. Its oral doses are likely to gain even more popularity in the near future.
